Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways

Mechanical ventilation can cause acute atrophy and injury in the diaphragm, which are related to adverse clinical results. However, the underlying mechanisms of ventilation-induced diaphragm dysfunction (VIDD)...

Source: BMC Pulmonary Medicine - December 14, 2023 Category: Respiratory Medicine Authors: Weimin Shen, Ye Jiang, Ying Xu, Xiaoli Qian, Jianwei Jia, Yuejia Ding, Yuhan He, Qing Pan, Jinyang Zhuang, Huiqing Ge and Peifeng Xu Tags: Research Source Type: research