Small proteins modulate ion-channel-like ACD6 to regulate immunity in Arabidopsis thaliana

The ankyrin-repeat transmembrane protein ACD6 was identified two decades ago, but its exact biochemical function has remained enigmatic. Chen et  al. show that ACD6 is a bona fide regulator of calcium influx using heterologous systems and calcium reporters in plants and that this activity can be further enhanced by a MHA1L peptide ligand.

Source: Molecular Cell - November 22, 2023 Category: Cytology Authors: Junbin Chen, Lei Li, Jong Hum Kim, Benjamin Neuh äuser, Mingyu Wang, Michael Thelen, Richard Hilleary, Yuan Chi, Luyang Wei, Kavita Venkataramani, Moises Exposito-Alonso, Chang Liu, Jakob Keck, A. Cristina Barragan, Rebecca Schwab, Ulrich Lutz, Zhen-Ming Tags: Article Source Type: research