Incorporating mutational heterogeneity to identify genes that are enriched for synonymous mutations in cancer

Synonymous mutations, which change the DNA sequence but not the encoded protein sequence, can affect protein structure and function, mRNA maturation, and mRNA half-lives. The possibility that synonymous mutati...

Source: BMC Bioinformatics - December 7, 2023 Category: Bioinformatics Authors: Yiyun Rao, Nabeel Ahmed, Justin Pritchard and Edward P. O ’Brien Tags: Research Source Type: research