Inferring disease architecture and predictive ability with LDpred2-auto

This study extends the utility of LDpred2-auto, a widely used method for deriving predictive polygenic scores. It validates the use of the latest version of LDpred2-auto for inferring key genetic parameters that inform us about the genetic architecture of traits, for identifying causal genetic variants, and for estimating predictive performance.

Source: The American Journal of Human Genetics - November 8, 2023 Category: Genetics & Stem Cells Authors: Florian Priv é, Clara Albiñana, Julyan Arbel, Bogdan Pasaniuc, Bjarni J. Vilhjálmsson Tags: Article Source Type: research