The soluble IL-2 receptor α/CD25 as a modulator of IL-2 function

We describe the molecular mechanisms leading to sIL-2Rα generation and discuss the different IL-2 modulating functions that have been attributed to the sIL-2Rα. Finally, we describe attempts to utilize the sIL-2Rα as a therapeutic tool.PMID:38037265 | DOI:10.1111/imm.13723

Source: Immunology - December 1, 2023 Category: Allergy & Immunology Authors: Juliane Lokau Lynn M Petasch Christoph Garbers Source Type: research