Sequenced-based GWAS for linear classification traits in Belgian Blue beef cattle reveals new coding variants in genes regulating body size in mammals

CONCLUSIONS: Our study further supports that a set of common genes controls body size across mammalian species. In particular, we added new genes to the list of those associated with height in both humans and cattle. We also identified new strong candidate causal variants in some of these genes, strengthening the evidence of their causality. Several breed-specific recessive deleterious variants were identified in our QTL regions, probably as a result of the extreme selection for muscular development in BBB cattle.PMID:38017417 | DOI:10.1186/s12711-023-00857-4

Source: Genet Sel Evol - November 29, 2023 Category: Genetics & Stem Cells Authors: Jos é Luis Gualdrón Duarte Can Yuan Ann-Stephan Gori Gabriel C M Moreira Haruko Takeda Wouter Coppieters Carole Charlier Michel Georges Tom Druet Source Type: research