Population Pharmacokinetics of Digoxin in Nonagenarian Patients: Optimization of the Dosing Regimen

ConclusionsThe greatest influence on digoxin clearance came from renal function calculated by the Cockcroft –Gault equation.Vd was decreased byK. The model developed showed a precise predictive performance to be applied for therapeutic drug monitoring.
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research