2136 The association of ABO and Rh blood groups with 30-day mortality following traumatic injury - a retrospective observational study

Conclusion 4188 patients were included. The median age was 59.3 [39.0-77.9] years, n=2634 (62.9%) were male, the median injury severity score was 19 [10-25], and 30-day mortality was 9.3%. Pairwise comparison demonstrated increased mortality in O Rh negative patients (Oneg) compared to three other groups, table 1. Compared to all other ABO Rh groups combined, Oneg patients had significantly greater 30-day mortality – 15.1% compared to 8.8%; RR 1.72 (95%CI 1.32-2.24), p=0.0002 (significance defined as p<0.0063 (eight comparisons)). There was no difference in admission PT or aPTT between Oneg and all other groups combined, p=0.12 and p=0.26 respectively. Trauma patients with Oneg had significantly greater 30-day mortality compared to other ABO Rh groups, which questions the existing hypothesis of the underlying mechanism. Abstract 2136 Table 1A pairwise comparison of 30-day mortality between all ABO Rh blood groups in n=4188 trauma patients at the East of England Major Trauma Centre (2016-2019)
Source: Emergency Medicine Journal - Category: Emergency Medicine Authors: Tags: RCEM Moderated Source Type: research