Longitudinal transitions between combustible, non-combustible, and poly-cannabis product use from adolescence to young adulthood and intersections with nicotine use

This study examined transitions across combustible and non-combustible form of cannabis use and poly-use from adolescence to young adulthood and the role of nicotine use in transitions. In a longitudinal cohort from Southern California (n=3,298; baseline mean[SD] age=16.1[0.4] years) with nine semi-annual survey waves (2015-2021), Markov multistate transition modeling estimated short (two-wave) and long-term (nine-wave) transition probabilities across five cannabis states: never use of any product, prior use with no past 6-month (P6M) use of any product, and P6M exclusive non-combustible, P6M exclusive combustible, and P6M poly product (non-combustible+combustible) use. Sizable transition probabilities from prior and exclusive P6M non-combustible or combustible cannabis use to P6M poly cannabis product use were observed in short (10.7%-38.9%) and long-term (43.4%-43.8%) analyses. P6M nicotine use increased risk of transitioning from never and prior use to exclusive P6M non-combustible and combustible cannabis use. Cannabis use in any form, even temporary use, during mid-adolescence may often be followed by poly cannabis product use. Nicotine use may amplify probability of future cannabis use onset or recurrence.PMID:37981712 | DOI:10.1093/aje/kwad230

Source: Am J Epidemiol - November 20, 2023 Category: Epidemiology Authors: Dae-Hee Han Junhan Cho Erin A Vogel Alyssa F Harlow Alayna P Tackett Sandrah P Eckel Rob McConnell Jessica L Barrington-Trimis Adam M Leventhal Source Type: research