Novel glycosyl prodrug of RXP03 as MMP-11 prodrug: design, synthesis and virtual screening
Like most phosphinic acids, the potent and selective RXP03 inhibitor of different MMPs exhibited moderate absorption and low bioavailability, which impaired its use. In an unprecedented attempt, we present an int...
Source: Chemistry Central Journal - Category: Chemistry Authors: Moaz M. Abdou, Ferenc Ötvös, Dewen Dong and Magdalini Matziari Tags: Research Source Type: research
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