Prognostic Implications of Chromosome 17 Abnormalities in the Context of Monosomal Karyotype in Patients With Acute Myeloid Leukemia and Complex Cytogenetics.

CONCLUSION: Among patients with CK-AML, MK was associated with poor outcomes. Additional presence of C17 abns further worsens the outcome in these particularly poor-risk patients with AML.
PMID: 24461514 [PubMed - as supplied by publisher]

Source: Clinical Lymphoma and Myeloma - January 21, 2014 Category: Cancer & Oncology Authors: Nazha A, Kantarjian HM, Bhatt VR, Nogueras-Gonzalez G, Cortes JE, Kadia T, Garcia-Manero G, Abruzzo L, Daver N, Pemmaraju N, Quintas-Cardama A, Ravandi F, Keating M, Borthakur G Tags: Clin Lymphoma Myeloma Leuk Source Type: research