TIGIT reverses IFN- α-promoted Th1-like Tregs via in-sequence effects dependent on STAT4

The induction direction of interferon (IFN)- α in T-cell phenotype and function varies depending on the activation state of the cell and the time of stimulation. To assess the effects of elevated IFN-α on regul...

Source: Arthritis Research and Therapy - November 17, 2023 Category: Rheumatology Authors: Shihan Yu, Jia Gu, Rui Wang, Seunghyun Lee, Yu Shan, Jiakai Wang, Yini Sun and Xiaoxue Ma Tags: Research Source Type: research