tRNA renovatio: Rebirth through fragmentation

Kuhle et al. explore tRNA-derived small RNAs (tsRNAs) as critical cellular regulators. Originating from tRNA “renovatio” (Latin for “renewal and rebirth”), tsRNA functions are tied to 3D structures and dynamically regulated by RNA modifications and binding partners, highlighting the promise of experimental and AI-based approaches to tackle their biological complexity.
Source: Molecular Cell - Category: Cytology Authors: Tags: Review Source Type: research