Optimal size threshold for PIRADSv2 category 5 upgrade and its positive predictive value: is it predictive of "very high" likelihood of clinically-significant cancer?

CONCLUSIONS: There is high correlation between MLD and LV with comparable discrimination of csPCA using each. PIRADSv2's 1.5 cm MLD threshold is near the optimal threshold for PIRADS 5 upgrade but has moderate PPV. A much higher threshold would be needed to increase its PPV, with significant sacrifice in sensitivity.PMID:37945438 | DOI:10.1016/j.crad.2023.10.008

Source: Clinical Prostate Cancer - November 9, 2023 Category: Cancer & Oncology Authors: V Batheja M Osman M Wynne D Nemirovsky G Morcos J Riess B Shin M Whalen S Haji-Momenian Source Type: research