Clinical significance of the expression levels of serum transforming growth factor- β and CXC type chemokine ligand 13 in primary Sjogren’s syndrome patients

ConclusionThe levels of TGF- β1 and CXCL13 in pSS patients were increased, and it was closely related to disease activity and lip gland pathological grading, which can be used as an effective indicator for the diagnosis of pSS.Key Points•The TGF- β1 and CXCL13 levels in the pSS group were higher than those in the control group.•The TGF- β1 and CXCL13 levels in pSS patients were positively correlated with disease activity and lip gland pathological grading.•TGF- β1 and CXCL13 can be used as an effective indicator for the diagnosis of pSS.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research