Introduction of ultra-hypofractionation in breast cancer: implications for costs and resource use

Radiotherapy (RT)1 is a core component of the comprehensive management of breast cancer, from early-stage disease to metastasis, and is used in 87% of the cases [1]. Traditionally, the standard regimen for early breast cancer consisted of the delivery of a total dose of 50 Gy in 25 fractions of 2 Gy over 5 weeks (i.e., conventional fractionation, CF) [2]. Over the last few years, however, a series of landmark randomised controlled clinical trials investigated the efficacy of administering larger doses per fraction in a shorter period of time.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research