Bruton ’s tyrosine kinase is a possible therapeutic target in microscopic polyangiitis

Bruton ’s tyrosine kinase (Btk) is an enzyme expressed in leukocytes other than T lymphocytes and plasma cells and involved in B-cell receptor- and Fcγ receptor (FcγR)-mediated signal transduction. Btk inhibito...

Source: Arthritis Research and Therapy - November 6, 2023 Category: Rheumatology Authors: Issei Nakade, Yuto Tamura, Fuyu Hashimoto, Yuko Ariza, Shingo Hotta, Hirofumi Fujigaya, Suishin Arai, Mai Taniguchi, Hodaka Ogawa, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Utano Tomaru and Akihiro Ishizu Tags: Research Source Type: research