95. Genomic profiling of a t(14;19) small B-cell lymphoma using whole exome sequencing

Small B-cell lymphomas are a diverse group of Non-Hodgkin lymphomas representing a clonal expansion of neoplastic B-cells. As molecular techniques evolve in clinical laboratories, this diverse group of tumors divides into more specific entities. Examples include MYD88 in lymphoplasmacytic lymphoma (LPL), t(14;18) in follicular lymphoma, and t(11;14) in mantle cell lymphoma. Less defined genetic changes include unusual translocations such as t(14;19), which has been reported in different subtypes of small B-cell lymphomas.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research