Ruthenium(II)-Catalyzed Selective C –H Bond Activation of Biindoles and Coupling with Sulfoxonium: An Efficient Access to Pyrido[1,2-a:4,3-b′]diindole frameworks

Synlett DOI: 10.1055/a-2179-6438 A ruthenium-catalyzed selective C–H functionalization/annulation cascade reaction of biindoles and sulfoxonium ylides has been developed. The reaction selectively provides pyrido[1,2-a:4,3-b′]diindole (5H-benzo[2,3]indolizino[7,8-b]indole) derivatives in good yields. A possible mechanism for the reaction pathway is proposed. More importantly, the present study provides a useful method for the construction of pyrido[1,2-a:4,3-b′]diindole frameworks. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Synlett - October 30, 2023 Category: Chemistry Authors: Jatoth, Ramanna Gugulothu, Kishan Valappil, Rasika Meloth Nelson, Nithya Kumar, K. Shiva Tags: letter Source Type: research