Approaching autozygosity in a small pedigree of Gochu Asturcelta pigs

CONCLUSIONS: Parameters characterizing homozygosity may not accurately depict losses of variability in small populations in which breeding policy prohibits matings between close relatives. After BP adjustment, the performance of FROH and FHRR was highly consistent. Assuming that an increase in homozygosity depends only on pedigree depth can lead to underestimating it in populations with shallow pedigrees. An increase in pairwise homozygosity computed from either FROH or FHRR is a promising approach for characterizing autozygosity.PMID:37880572 | PMC:PMC10601182 | DOI:10.1186/s12711-023-00846-7

Source: Genet Sel Evol - October 25, 2023 Category: Genetics & Stem Cells Authors: Katherine D Arias Juan Pablo Guti érrez Iv án Fernández Isabel Álvarez F élix Goyache Source Type: research