99mTc generator using molybdenum nanoparticles

AbstractA novel99mTc generator was proposed herein using nanoparticles consisting of natural Mo and an alumina column for99mTc scintigraphy.99mTc was obtained from99Mo decay produced via the irradiation of nanoparticles consisting of natural Mo with bremsstrahlung γ-rays using a 30 MeV electron beam. The irradiated nanoparticles were placed in an alumina column, and the99mTc daughter from99Mo decay was separated by the removal of the ion-exchanged water or saline. This separation procedure was repeated at regular intervals for one week. The maximum separation yield of99mTc was 14.4  ± 0.7%, which is sufficiently high to produce99mTc suitable for medical use.
Source: Journal of Radioanalytical and Nuclear Chemistry - Category: Nuclear Medicine Source Type: research