Link Stress-Related Gut Microbiota Shifts to Mental Health Outcomes

Stress levels are surging, alongside the incidence of stress-related psychiatric disorders. Perhaps a related phenomenon, especially in urban areas, the human gut contains fewer bacterial species than ever before. Although the functional implications of this absence is unclear, one consequence may be reduced stress resilience. Preclinical and clinical evidence has shown how stress exposure can alter the gut microbiota and their metabolites, affecting host physiology. Also, stress-related shifts in the gut microbiota jeopardize tight junctions of the gut barrier.

Source: Biological Psychiatry - October 28, 2023 Category: Psychiatry Authors: Annelise A. Madison, Michael T. Bailey Tags: Review Source Type: research