Sinomenine Ameliorates IL-1 β-Induced Intervertebral Disc Degeneration in Rats Through Suppressing Inflammation and Oxidative Stress via Keap1/Nrf2/NF-κB Signaling Pathways

CONCLUSION: SN can prevent IL-1β-induced apoptosis of NPCs and ameliorate IDD by activating the Keap1/Nrf2 pathway and inhibiting the NF-κB signaling pathway.PMID:37881650 | PMC:PMC10596063 | DOI:10.2147/JIR.S430423

Source: Cell Research - October 26, 2023 Category: Cytology Authors: Gongbiao Lu Cunxin Zhang Kang Li Kai Gao Maoqing Fu Chaoliang Lyu Zhengxue Quan Source Type: research