Oral Malassezia infection co-occurring with tinea versicolor: Metagenomic sequencing of the saliva

Malassezia is a lipid-dependent cutaneous symbiotic fungal genus associated with tinea versicolor. Here, we first present a rare case of a young tinea versicolor patient with oral manifestations presenting as white strips, patches, and pigmentation. The patient had a family history of tinea versicolor and a habit of frequent intake of cream. Histopathologic features and periodic acid-schiff staining of oral lesion indicated oral infection with round budding yeasts with short hyphae. Saliva metagenomic sequencing identified Malassezia and demonstrated the upregulated amount, diversity and activity of inflammatory bacteria.

Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - October 25, 2023 Category: ENT & OMF Authors: Qin Jiang, Jing Zhang, Gang Zhou Source Type: research