Human macrophages choreograph tissue development

Trends Immunol. 2023 Oct 11:S1471-4906(23)00206-5. doi: 10.1016/j.it.2023.09.010. Online ahead of print.ABSTRACTYolk sac-derived macrophages have been described to promote organogenesis and tissue function in animal models, but the relevance of these studies for humans has been debated. Wang et al. reveal that human macrophage development follows similar developmental trajectories with functionally distinct macrophage populations across tissues as observed in mice.PMID:37833121 | DOI:10.1016/j.it.2023.09.010
Source: Trends in Immunology - Category: Allergy & Immunology Authors: Source Type: research