Strain assessment in aortic stenosis: pathophysiology and clinical utility

Contemporary echocardiographic criteria for grading aortic stenosis severity have remained relatively unchanged despite significant advances in non-invasive imaging techniques over the last two decades. More recently, attention has shifted to the ventricular response to aortic stenosis and how this might be quantified. Global longitudinal strain (GLS), semi-automatically calculated from standard 2D echocardiographic images, has been the focus of extensive research. GLS is a sensitive marker of subtle hypertrophy-related impairment in left ventricular function and has shown promise as a relatively robust prognostic marker, both independently and when added to severity classification systems.
Source: Journal of the American Society of Echocardiography - Category: Cardiology Authors: Tags: Review Articles Source Type: research