Synthesis, crystal structure and in vitro anti-proliferative activity of 2-[(4-acetylphenyl)carbamoyl]phenyl acetate

2-[(4-Acetylphenyl)carbamoyl]phenyl acetate, C17H15NO4, has been synthesized and structurally characterized. In the structure, N — H...O hydrogen-bonding interactions form chains of molecules aligned along the [101] direction. The chains are linked by π – π and C — H... π interactions, forming a three dimensional network. The compound has been screened for in vitro anti-proliferative activity revealing considerable activity.

Source: Acta Crystallographica Section E - October 5, 2023 Category: Chemistry Authors: Mohamed-Ezzat, R.A. Kariuki, B.M. Srour, A.M. Tags: crystal structure aspirin derivative NCI 60 cell line anti-proliferative activity research communications Source Type: research