A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells

Magkouta et  al. describe a marker for senescence detection (GLF16) that surpasses limitations of previously established markers (SA-β-Gal and GL13). Apart from in vitro analyses, GLF16 is particularly suitable for in vivo identification, isolation, and downstream characterization of senescent cell populati ons at the single-cell level in various biological materials.

Source: Molecular Cell - October 5, 2023 Category: Cytology Authors: Sophia Magkouta, Dimitris Veroutis, Athanasios Pousias, Angelos Papaspyropoulos, Natassa Pippa, Nikolaos Lougiakis, Konstantinos Kambas, Nefeli Lagopati, Aikaterini Polyzou, Maria Georgiou, Maria Chountoulesi, Stergios Pispas, Spyros Foutadakis, Nicole Po Tags: Technology Source Type: research