Correlation between synthetic MRI relaxometry and apparent diffusion coefficient in breast cancer subtypes with different neoadjuvant therapy response

ConclusionsThe relationship between ADC and PD maps in TNBC may indicate different NAT responses. The no-to-weak correlation between the ADC and syMRI suggests their complementary roles in tumor microenvironment evaluation.Critical relevance statementThe relationship between ADC and PD maps in TNBC may indicate different NAT responses, and the no-to-weak correlation between the ADC and syMRI suggests their complementary roles in tumor microenvironment evaluation.Key points• The relationship between ADC and PD in TNBC indicates different NAT responses.• The no-to-weak correlations between ADC and syMRI complementarily evaluate tumor microenvironment.• T2 low percentiles and median predict NAT response in luminal-HER2-negative subtype.Graphical Abstract

Source: Insights into Imaging - September 29, 2023 Category: Radiology Source Type: research