Re-evaluating the mosquito RNAi pathway's influence on arbovirus transmission

Trends Parasitol. 2023 Sep 25:S1471-4922(23)00226-X. doi: 10.1016/j.pt.2023.09.005. Online ahead of print.ABSTRACTWith new RNA interference (RNAi) pathway-deficient mosquitoes, Merkling et al. invite a shift in our view of this pathway's role in regulating arthropod-borne virus (arbovirus) transmission. While loss of RNAi function enhanced early viral replication, little impact on transmission was observed, inviting renewed exploration of molecular barriers to arbovirus transmission.PMID:37758630 | DOI:10.1016/j.pt.2023.09.005

Source: Trends in Parasitology - September 27, 2023 Category: Parasitology Authors: Kevin Maringer Source Type: research