Clinico-genomic profiling of conventional and dedifferentiated chondrosarcomas reveals TP53 mutation to be associated with worse outcomes

CONCLUSION: IDH mutations are prevalent in chondrosarcoma though were not associated with survival outcomes in this cohort. TP53 mutations were the next most common alteration and were associated with worse outcomes.PMID:37747813 | DOI:10.1158/1078-0432.CCR-23-1703

Source: Clinical Cancer Research - September 25, 2023 Category: Cancer & Oncology Authors: Ryan A Denu Richard K Yang Alexander J Lazar Shalin S Patel Valerae O Lewis Jason Roszik J Andrew Livingston Wei-Lien Wang Kenna R Shaw Ravin Ratan Maria A Zarzour Justin Bird Shaan M Raza Kadir C Akdemir Jordi Rodon Ahnert Vivek Subbiah Shreyaskumar Pate Source Type: research