Two cases of successful sirolimus treatment for patients with activated phosphoinositide 3-kinase δ syndrome 1

Activated phosphoinositide3-kinase (PI3K) δ syndrome 1 (APDS1) is a novel inborn errors of immunity (IEIs) caused by heterozygous gain of function mutations in PI3Kδ catalytic p110δ (PIK3CD). APDS1 has a spect...

Source: Allergy, Asthma and Clinical Immunology - September 23, 2023 Category: Allergy & Immunology Authors: Lu Jiang, Xiaohan Hu, Qiang Lin, Ruyue Chen, Yunyan Shen, Yun Zhu, Qinying Xu and Xiaozhong Li Tags: Case report Source Type: research