Z-ligustilide preferentially caused mitochondrial dysfunction in AML HL-60 cells by activating nuclear receptors NUR77 and NOR1

Nuclear receptors NUR77 and NOR1 were identified as critical targets in acute myeloid leukemia (AML) therapy. Previously, we showed that Z-ligustilide (Z-LIG) selectively targeted AML by restoring NUR77 and NO...

Source: Chinese Medicine - September 21, 2023 Category: Complementary Medicine Authors: Gen Liu, Zhi-gang Chen, Li-rong Yang, Yu-xia Rong, Qin Wang, Li Li, Qian-wei Lu, Ming-dong Jiang and Hong-yi Qi Tags: Research Source Type: research