Stevens-Johnson syndrome and toxic epidermal necrolysis – 11-year retrospective experience in a high complexity tertiary hospital in Milan, Italy

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug-induced hypersensitivity reactions characterized by widespread epidermal necrosis, mucous membrane erosions, and systemic findings. We have provided our 11-year experience from a Milan, Italy tertiary hospital managing SJS/TEN, evaluating the clinical and histopathologic features plus the impact on mortality. We retrospectively analyzed 28 patients diagnosed with SJS/TEN based on the clinical and histopathologic findings, according to the classification criteria of Bastuji-Garin et al 1,2.

Source: Clinics in Dermatology - September 14, 2023 Category: Dermatology Authors: Jan W Schroeder, Valentina Caputo, Stefania Guida, Francesca Conte, Giovanni Paolino, Emanuela Bonoldi, Franz W Baruffaldi-Preis, Franco Rongioletti Source Type: research