A New Acridone Alkaloid from the Leaves of Glycosmis lucida

Extraction and chromatographic separation of the extracts of dried leaves ofGlycosmis lucida lead to the isolation of a new acridone alkaloid lucidaine A (1), along with two known analogues2 and3. The structure of1 was established by extensive spectroscopic analysis (1D and 2D NMR, HR-ESI-MS), and the known compounds were identified by comparisons with data reported in the literature. Furthermore, the cytotoxicity activities of all isolated alkaloidsin vitro were evaluated.

Source: Chemistry of Natural Compounds - September 13, 2023 Category: Chemistry Source Type: research