PhaseDancer: a novel targeted assembler of segmental duplications unravels the complexity of the human chromosome 2 fusion going from 48 to 46 chromosomes in hominin evolution

Resolving complex genomic regions rich in segmental duplications (SDs) is challenging due to the high error rate of long-read sequencing. Here, we describe a targeted approach with a novel genome assembler Pha...

Source: Genome Biology - September 11, 2023 Category: Genetics & Stem Cells Authors: Barbara Poszewiecka, Krzysztof Gogolewski, Justyna A. Karolak, Pawe ł Stankiewicz and Anna Gambin Tags: Method Source Type: research