The searchable chromosome

Trends Genet. 2023 Sep 8:S0168-9525(23)00188-9. doi: 10.1016/j.tig.2023.08.006. Online ahead of print.ABSTRACTTo date, genome structure and dynamics have been studied mostly independently; their interplay is a notable blind spot of the field. Brückner, Chen, et al. recently demonstrated an integrated experimental approach sensitive to both, uncovering a striking robustness of enhancer-promoter search times (dynamics) to changes in genomic separation (structure).PMID:37690888 | DOI:10.1016/j.tig.2023.08.006

Source: Trends in Genetics : TIG - September 10, 2023 Category: Genetics & Stem Cells Authors: Simon Grosse-Holz Source Type: research