Mechanisms and rationale for uricase use in patients with gout

Nature Reviews Rheumatology, Published online: 08 September 2023; doi:10.1038/s41584-023-01006-3In this Review, the authors provide an overview of the therapeutic effects of uricases, outcomes related to gout and its comorbidities in clinical trials and challenges surrounding the use of uricases as potent urate-lowering therapy for the treatment of gout.

Source: Nature Reviews Rheumatology - September 8, 2023 Category: Rheumatology Authors: Naomi Schlesinger Fernando P érez-Ruiz Fr édéric Lioté Source Type: research