Optical Co-Registration Method of Triaxial OPM-MEG and MRI

In this study, we proposed a triaxial co-registration method according to combined principal component analysis and iterative closest point algorithms for use of a flexible cap. A reference phantom with known sensor positions and orientations was designed and constructed to evaluate the accuracy of the proposed method. Experiments showed that the average co-registered position errors of all sensors were approximately 1 mm and average orientation errors were less than 2.5° in the ${X}$ -and ${Y}$ orientations and less than 1.6° in the ${Z}$ orientation. Furthermore, we assessed the influence of co-registration errors on the source localization using simulations. The average source localization error of approximately 1 mm reflects the effectiveness of the co-registration method. The proposed co-registration method facilitates future applications of triaxial sensors on flexible caps.
Source: IEE Transactions on Medical Imaging - Category: Biomedical Engineering Source Type: research