Anticholinergic Burden and Cognitive Impairment in Nursing Homes: A Comparison of Four Anticholinergic Scales

ConclusionsThe cumulative effect of medications with modest antimuscarinic activity may influence the cognitive performance of NH residents. The anticholinergic burden measured with the ACB scale should help identify NH residents who may benefit from reducing the anticholinergic burden.A clear direct relationship between anticholinergic burden and cognitive impairment was found only for the ACB Scale.
Source: Drugs and Aging - Category: Geriatrics Source Type: research