Feel so bac: is Fusobacterium the suspect causing endometriosis?

Trends Mol Med. 2023 Aug 18:S1471-4914(23)00188-0. doi: 10.1016/j.molmed.2023.08.003. Online ahead of print.ABSTRACTRecent work by Muraoka and colleagues reports that the Gram-negative anaerobic bacterium Fusobacterium nucleatum is detected in the uterus of 64% of women with endometriosis. Fusobacterium infection causes macrophage infiltration, transforming growth factor-β production, and transgelin upregulation in human and mouse endometria as well as endometriotic lesion development in a mouse model of endometriosis.PMID:37599125 | DOI:10.1016/j.molmed.2023.08.003
Source: Trends in Molecular Medicine - Category: Molecular Biology Authors: Source Type: research