Fibroblast multiplicity in RA: a synovial state of affairs

Nature Reviews Rheumatology, Published online: 21 August 2023; doi:10.1038/s41584-023-01015-2Rheumatoid arthritis synovium contains phenotypically and functionally heterogeneous fibroblast-like synoviocytes. Cutting-edge analyses have now defined at least four distinct states of these cells related to their location in the synovium, epigenetic imprinting and the influence of microenvironment mediators.

Source: Nature Reviews Rheumatology - August 21, 2023 Category: Rheumatology Authors: Camilla R. L. Machado Gary S. Firestein Source Type: research