Potential roles for lncRNA Mirg/Foxp1 in an ARHL model created using C57BL/6J mice

In conclusion, our findings suggest that lncRNA Mirg expression correlates with cell apoptosis-associated mRNAs in the ARHL model created using C57BL/6 J mice and that oxidative stress-induced lncRNA Mirg promotes HEI-OC1 cell apoptosis by increasing Foxp1 expression. These data suggest the potential therapeutic significance of targeting lncRNA Mirg/Foxp1 signaling in ARHL.PMID:37579646 | DOI:10.1016/j.heares.2023.108859

Source: Hearing Research - August 14, 2023 Category: Audiology Authors: Xiaoqin Luo Yaqin Hu Xiaoqing Zhou Chanyuan Zhang Menglong Feng Ting Yang Wei Yuan Source Type: research