Potential Implication of HLA-DQ Heterodimer High-Resolution Typing on Kidney Transplant Outcomes and Equity

AbstractPurpose of ReviewTo evaluate the potential implications of HLA-DQ αβ heterodimer high-resolution typing on clinical decision-making in solid organ transplantation.Recent FindingLack of HLA-DQ αβ heterodimer high-resolution typing information impacts cPRA calculations for patients on the waitlist and thus can affect their priority in organ allocation algorithms. It can further affect the number of potential compatible organ offers that they can receive.SummaryWe believe that the compiled data highlight the need for a thorough evaluation by the OPTN/UNOS, to assure equity for patients in need of organ transplantation.
Source: Current Transplantation Reports - Category: Transplant Surgery Source Type: research