Neuronal tau pathology worsens late-phase white matter degeneration after traumatic brain injury in transgenic mice

Conclusions: Neuronal tau pathology differentially exacerbated CC pathology based on i njury severity and chronicity. Ongoing CC atrophy from s-TBI became accompanied by late demyelination. Pathological tau significantly worsened CC atrophy during the chronic phase after r-mTBI.
Source: Acta Neuropathologica - Category: Neurology Source Type: research