Elevated circulating CD19 < sup > + < /sup > CD24 < sup > hi < /sup > CD38 < sup > hi < /sup > B cells display pro-inflammatory phenotype in idiopathic membranous nephropathy

In conclusion, CD19+CD24hiCD38hi B cells were expanded but functionally impaired in IMN patients. Their altered pro-inflammatory cytokine profile may contribute to the pathogenesis of IMN.PMID:37553031 | DOI:10.1016/j.imlet.2023.08.001

Source: Immunology Letters - August 8, 2023 Category: Allergy & Immunology Authors: Bishun Deng Li Deng Miao Liu Ziling Zhao Huijie Huang Xiaoxin Tu Enyu Liang Ruimin Tian Xiaowan Wang Rongrong Wang Haibiao Lin Yongyi Yu Anping Peng Peng Xu Kun Bao Min He Source Type: research