Plasma signatures of Congenital Generalized Lipodystrophy patients identified by untargeted lipidomic profiling are not changed after a fat-containing breakfast meal

Congenital Generalized Lipodystrophy (CGL), also known as Berardinelli-Seip congenital lipodystrophy, is an autosomal recessive disorder characterized by severe loss of adipose tissue, approaching total tissue absence since birth or in early infancy [1]. Life expectancy is significantly shortened in CGL [2].

Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - July 31, 2023 Category: Biomedical Science Authors: Camilla O.D. Ara újo, Amanda P. Pedroso, Valter T. Boldarine, Anna Maria A.P. Fernandes, José J.M. Perez, Renan M. Montenegro, Ana Paula D.R. Montenegro, Annelise B. de Carvalho, Virgínia O. Fernandes, Lila M. Oyama, Patrícia O. Carvalho, Carla S.C. M Source Type: research