Biflavonoids from Selaginella trichoclada

Thirteen robustaflavones (1 –13) were isolated from the 70% EtOH extract of Selaginella trichoclada Alston herbs for the first time. The structures of these compounds were identified on the basis of extensive spectroscopic data including UV-vis, 1D and 2D NMR, and mass spectra. The molecular docking results indicate that the robustaflavone derivates may play a role as a NEDD4 protein inhibitor.

Source: Chemistry of Natural Compounds - July 31, 2023 Category: Chemistry Source Type: research