Synthesis of New 9-Substituted Derivatives of 2-Oxomethylcytisine

New derivatives of 3-methylcytisine with 9-aromatic substituents bonded to the pyridone core of the starting alkaloid through spacers of various natures, e.g., aminomethyl, amide, thio- and carboxamide, ethenyl, and ethyl, were synthesized from 9-amino- and 9-bromo-2-oxomethylcytisine.

Source: Chemistry of Natural Compounds - July 31, 2023 Category: Chemistry Source Type: research