E-104 Inhibiting the neuron-immune axis in acute ischemic stroke reverses microglia-induced neuroinflammation after reperfusion

ConclusionTogether, these findings indicate that ischemic/hypoxic-induced neuronal excitotoxicity promotes neuroinflammation in the setting of reperfusion after ischemic stroke. Inhibiting abnormal neuronal activation triggered by ischemia may prevent microglia-induced neuroinflammation that could protect the brain from secondary brain damage.Disclosures X. Guo: None. D. Xin: None. W. Qiu: None. G. Li: None. Z. Wang: None.

http://jnis.bmj.com/cgi/content/short/15/Suppl_1/A138-a?rss=1

Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Guo, X., Xin, D., Qiu, W., Li, G., Wang, Z. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research